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This product contains HFC-152a (GWP = 124)

and FDA issues new regulations on e-cigarettes and other products On June 9th, California becomes the second state to change its tobacco minimum-age sales law to 21 years old for tobacco, e-cigarettes and vaping products.* Hawaii changed to 21 at the beginning of 2016

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Chronic nicotine use leads to the upregulation of 42 nAChRs, the main nicotinic acetylcholine receptor subtype promoting addiction (Papke et al., 2020), producing an important difference in brain activity between smokers and non-smokers