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The lower the inspiratory muscle strength, the better the IMT response, especially when associated with overall exercise training (Hoffman et al., 2021)

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The TSNA compounds exclusively 3-[(2S)-1-Nitrosopyrrolidin-2-yl] pyridine (NNN) and Methyl [4-oxo-4-(pyridin-3-yl) butyl] nitrous amide (NNK) has been categorized as Group I carcinogens (known human carcinogens) by the IARC (IARC 2012)

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