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PMID 39821398

The FDA should list such products as pending scientific review in its searchable tobacco products database 46 and agree to use its enforcement discretion to not take enforcement action against products still in review because of unlawful delays in the FDAs evaluation
Increased expression of genes such as MMP12 and SPP1 in the lung resembled COPD-like alterations, while intestinal gene changes (CD79B, PAX5) paralleled those in Crohns disease

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