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doi: 10.1371/journal.pone.0057987 133

While there is currently no limit on the level of nicotine exposure that applies to every person who can become addicted, this begs the question of what level of nicotine reduction can prevent smokers from becoming addicted and what level of nicotine reduction can help established smokers readily control or quit their use

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Customised search strings were created and employed to locate relevant studies, the details of which are provided in Supplementary Material

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