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The two drug classes share the goal of weight loss but achieve it through fundamentally different biological pathways, which is precisely why they have different efficacy profiles, side effects, and treatment durations

In both areas, the amount of excess skin generally tracks with the amount of lost weight, meaning the more weight that is lost, the more excess skin that is usually left behind, Burns adds

doi: 10.1079/bjn20051545

Semaglutide is a GLP-1 receptor agonist that mimics a natural hormone, helping to reduce appetite, slow digestion, and improve blood sugar control

A patient who is pregnant, planning pregnancy, or becomes pregnant while receiving treatment should speak with the prescribing clinician promptly

Doug Langa, executive vice president, head of North America operations and president, Novo Nordisk US, attributes this giddying momentum to a one-team approach. The drug had already sped quickly through the FDA approval process thanks to a priority review voucher