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however, there are rare but serious risks, such as mood changes, cardiovascular events (especially in at-risk individuals), seizures, and severe allergic reactions

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Limitations One of the major limitations of this review is its reliance on cross-sectional studies, since longitudinal ones are necessary to establish casual relationships between smoking and sleep disturbances

A meta-analysis suggests that varenicline is an effective relapse prevention intervention for individuals who have recently become abstinent in response to a prior smoking cessation treatment