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Long-term exposure may lead to liver and kidney damage, as well as respiratory problems

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Nicotine's Effect on Brain Chemistry For years, nicotine has been manipulating your brain chemistry in ways you never felt: Dopamine manipulation: Nicotine triggers dopamine release, creating artificial feelings of alertness and focus
[DOI] [PMC free article] [PubMed] [Google Scholar] 70.Padureanu V, Fortofoiu MC, Pirscoveanu M, Padureanu R, Radulescu D, Donoiu I, et al
