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"The consequences of these reduced MAO-B levels need to be examined in greater detail," declared Fowler, "but, at the very least, it is clear that enzyme levels in smokers' peripheral organs are significantly impacted by their habit." One of the functions performed by MAO in the body is to break down chemical compounds that elevate blood pressure, such as chemicals found in certain foods like cheese and wine, as well as some chemicals that are released by nicotine
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Nicotine products seem to come in waves of popularity, from the boom of cigarette smoking to the rise of vaping

Metric and Insights LLC, , A Nationwide Survey Among General Population Adults, February 2023, 8

In a recent genome-wide association study (GWAS) of smoking, smoking initiation and severity, and BD no genetic correlation could be established whereas smoking and schizophrenia appeared genetically correlated (20)

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