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Staley JK, Krishnan-Sarin S, Cosgrove KP, Krantzler E, Frohlich E, Perry E et al (2006)

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Another ligand for RAGE is the nuclear protein high-mobility group box-1 (HMGB1), which is normally buried deep within the nucleus and can be released into the extracellular space by passive diffusion from necrotic cells or by active secretion from activated macrophages/monocytes

London Southend Airport Use of e-cigarettes is not permitted within the airport buildings

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adolescentssmokers and non-smokers alikeare aware of the long-term health effects of smoking. According to recent surveys, 95% of the population in 1990 believed that smoking is a health risk for lung cancer (Kenkel & Chen, 2000), and most people actually overestimate the harm of smoking (Viscusi, 1992)