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CrossRef Examination of the TPMT and NUDT15*3 Variants to Predict the Response to Thiopurines in an Italian Cohort of Patients with Inflammatory Bowel Disease Francesca Tavano, Orazio Palmieri, Maria Latiano, Domenica Gioffreda, Tiziana Latiano, Maria Guerra, Giuseppina Martino, Maria Rosa Valvano, Fabrizio Bossa, Francesco Perri, Anna Latiano International Journal of Molecular Sciences.2025

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These lineages are characterized by deep divergence, minimal genomic evidence of ongoing migration and signatures of local adaptation

And the forest was coming closer, sometimes intruding into the settlement