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The thermal degradation of sugars can produce toxic furans, such as 5-hydroxymethylfurfural and furfural

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The data were self-reported, which can sometimes be inaccurate

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2025 We demonstrated that this association was likely due to smoking behavior resulting in increased uptake of nicotine and the lung carcinogen NNK in carriers of these variants, as determined by quantitation of nicotine metabolites and the NNK metabolite total NNAL in urine

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