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This is because CO displaces O 2 from hemoglobin forming carboxyhemoglobin (CO affinity for hemoglobin is 200 times that of O 2 ) and shifting the oxygen dissociation curve to the left, thereby causing hypoxia and impairment of cellular respiration [76]

Quantitative analysis was performed using a 7890B/5977A gas chromatography/mass spectrometry system (Agilent Technologies

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[143] A CHA 2 DS 2 -VASc score of zero is considered very low risk

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