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Offenses such as possessing, selling, or distributing e-cigarettes containing prohibited substances (e.g., etomidate) now carry penalties including up to 20 years in prison and 15 strokes of the cane

excessive richness of nutrients in a lake or other body of water, frequently due to runoff from the land, which causes a dense growth of plant life and death of animal life from lack of oxygen

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The following primary antibodies were used: anti-ATP7A (Santa Cruz Biotechnologies, Texas, USA, sc-376467), anti-CTR1 (abcam, Massachusetts, USA, #ab129067), anti-ABCG2 (Cell Signaling Technology, Massachusetts, USA, #42078), and -actin as a loading control (Cell Signaling Technology, Massachusetts, USA, #8457)
