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Together these two mechanisms explain why smoking consistently produces comedonal acne even in people without typical hormonal acne patterns the androgenic sebum stimulation and the oxidative sebum peroxidation create the follicular environment for comedone formation independently of the inflammatory immune response that drives pustular and cystic acne

[6] Exposure to nicotine and its great risk of developing an addiction, are areas of significant concern

1 / 14 Stress Long-term stress floods your body with cortisol, a hormone that plays a part in your fight or flight system

There are 100 smokers for every vejper

J Pharmacol Exp Ther (1987) 242(1):2327

[DOI] [PMC free article] [PubMed] [Google Scholar] 11.Chen RJ, Chang LW, Lin P, Wang YJ