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Environ Sci Pollut Res Int 29:7762577634 Sadler NC, Webb-Robertson BM, Clauss TR, Pounds JG, Corley R, Wright AT (2018) High-fat diets alter the modulatory effects of xenobiotics on cytochrome P450 activities

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This iron [dysregulation] drives oxidative stress, mitochondrial dysfunction, and increased -synuclein [protein] expressionhallmarks of neurodegenerative disease, Chen said

To assess the most significant among these, this paper follows the guidelines of Fowles and Dybing (6), who suggested identifying chemical components with the greatest potential for toxic effects, specifically those associated with cancer, respiratory, and cardiovascular diseases

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