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[DOI] [PubMed] [Google Scholar] [94].Flint DH, Tuminello JF, Emptage MH

Phosphorylation of Parkin at serine 131 by p38 MAPK promotes mitochondrial dysfunction and neuronal death in mutant A53T -synuclein model of Parkinsons disease

A further novel finding is that artesunate promoted the activity of catalase and decreased the nicotinamide adenine dinucleotide phosphate (NADPH) protein levels, artesunate inhibited the PI3K and p42/22 MAPK signaling pathways along the way (Ng et al., 2014)

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The protein bands were acquired through ECL chemiluminescence and quantified and standardized using ImageJ software v1.8.0

doi: 10.1126/science.1096284 225 WeindelCGBellSLVailKJWestKOPatrickKLWatsonRO