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Despite the lack of carcinogenicity evidence, it has been reported that nicotine promotes tumour cell survival by decreasing apoptosis and increasing proliferation [49], indicating that it may work as a tumour enhancer

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Keywords: Nicotine, biochemistry, lipid profile, hematology, histology, Labeo rohita Introduction Nicotine and tobacco delivery products have been used in the past decade as alternatives to traditional tobacco products that are less harmful, e.g., tobacco heating products, e-cigarettes, and oral nicotine pouches [1]