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10: Ch 1, Repeat row 9

However, misleading claims (ie, organic, natural, and additive-free) were much more likely to have any impact than disclaimers

8 Ceramide supplementation eliminates the beneficial effects derived from intestinal AMPK1 deficiency

4,942 1,601 6,543 223 6,766 6,766 +5.9 % AME 3,433 (128) 3,305 72 3,377 (308) 3,069 +9.6 % APMEA 1,622 102 1,724 69 1,793 1,793 -17.9 % Total Region 9,997 1,575 11,572 364 11,936 (308) 11,628 +2.3 % Net finance costs (1,819) 170 (1,649) (27) (1,676) (57) (1,733) +1.0 % Associates and joint ventures 1,681 (1,239) 442 33 475 475 -8.6 % Profit before tax 9,859 506 10,365 370 10,735 (365) 10,370 +1.9 % Taxation (2,094) (344) (2,438) (84) (2,522) 97 (2,425) +1.3 % Non-controlling interests (1) (125) (126) (3) (129) (129) -14.1 % Coupons relating to hybrid bonds net of tax (87) 29 (58) (58) (58) +36.9 % Profit attributable to shareholders 7,677 37 7,743 283 8,026 (268) 7,758 +2.2 % Diluted number of shares (m) 2,199 2,199 2,199 2,199 -1.2 % Diluted earnings per share (pence) 349.1 352.1 365.0 (12.2) 352.8 +3.4 % 2024 at actual (2024) rates For year ended 31 December 2024 Reported Adj Items1 Adjusted Ad