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Pipe tobacco is blended for richer flavour, has a coarser cut, and burns more slowly, making it suitable for use in a pipe

discovered, in 1998, a positive association between PBD and alleles HLA-A11, HLA-B54, and HLA-Cw1, while HLA-A33 and HLA-B44 increased their frequencies in the control groups, suggesting a protective association for these alleles in Japanese populations 112

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For optimal performance, fill with Zippo lighter fuel

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