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cigarette smoke induces cytoplasmic p53 accumulation The role of p53-mediated signaling pathways in nicotine-induced cancer: a systematic review Tobacco smoke carcinogens, DNA damage
Description
The bilateral effects of p53 on autophagy are considered to be related to its intracellular localization
Abstract Tobacco smoke negatively affects human bronchial epithelial (HBE) cells and is directly implicated in the etiology of smoking related respiratory diseases
doi: 10.1111/j.1751-1097.2010.00815.x
(3) p53 can induce apoptosis by promoting the expression of the downstream transcriptional target Perp (p53 apoptosis effector related to PMP-22)
Cell Dev
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