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Is it the base chemicals that are in the [vaporized] liquid

After the liquid has been used up, the device is no longer serviceable

The incidence rate of metabolic syndrome among never EVC users was 336.1/100000 PMs, and the incidence rate among never HTP users was 325.7/100000 PMs, higher than the incidence rate among never smokers of conventional cigarettes (253.8/100000 PMs), likely reflecting dual use

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(Interestingly, history is repeating itself now with the increasing popularity of e-cigarettes, which produce several vaporized chemicals, have no regulatory oversight, and contain varying amounts of nicotine.) Cigarette smoke is a complex mixture of gases and submicron-size particulate matter [35]