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Directed evolution of the luciferase from the deep-sea shrimp Oplophorus gracilirostris led the creation of NanoLuc luciferase in 2012, which has since been used for a variety of research, ranging from clinical drug development to studies of neurodegenerative diseases

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Poly(dimethylsiloxane) (PDMS), a standard polymeric material used for the fabrication of microfluidic devices by master-replication techniques, was already shown to allow a site-specific bottom-up integration of TMV carrier sticks [60]