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Levels of thrombomodulin, which is produced by the vascular endothelium and has anticoagulant effects, were higher in nonsmoking offspring of smokers, but levels of von Willebrand factor were unchanged

Another comprehensive review placed the risk at roughly triple for smokers versus nonsmokers, alongside greater bone deterioration and a diminished response to treatment overall

University of Maryland Labor History Collection, Special Collections and University Archives.

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Cigarette smoking and the risk of systemic lupus erythematosus, overall and by anti-double-stranded DNA antibody subtype, in the Nurses Health Study cohorts
