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Prolonged use alters brain chemistry, resulting in physical dependence and the necessity for higher doses to achieve the desired calming effects

On the plus side, if this does happen, Cigar Oasis are usually happy to send out replacement units

[DOI] [PMC free article] [PubMed] [Google Scholar] 229.World Health Organization

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College Campus Tobacco Policies Database is a proprietary policy surveillance tool created by the ANR Foundation for the systematic collection and analysis of current policies governing smokefree and tobacco-free college campuses within the continental United States and territories, including adjacent American Indian and Alaska Native sovereign tribal entities