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In multivariable MR analyses adjusting for sleep duration, alcohol consumption, body mass index and smoking alone ( Supplementary Tables S5 - 8 ) or together ( Figure 3 ), we found only ASOM to be associated with T2DM from both databases (In NHGRI-EBI: OR = 1.09, 95%CI: 1.03-1.16, P = 0.005

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The Chongzhen Emperor of China issued an edict banning smoking two years before his death and the overthrow of the Ming dynasty

Within each alcohol group, current smokers had the highest age adjusted relative rate for all cause mortality and ex-smokers had higher relative rates than never smokers