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Patterns of exclusive and combined CC, EC and HTP use are detailed in Figure 1 and Supplementary file Table 2

Shiffman et al., 2004) have demonstrated expected associations, for example, between alcohol and smoking and between craving and smoking but have also yielded some surprising findings, notably the lack of an association between smoking and mood during ad lib smoking

Its unclear whether she had been a regular smoker, although even light tobacco use can increase risks

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While many major brands have removed diacetyl, not all products are tested or regulated, especially in online or black-market sales