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Tinnitus typically begins with peripheral auditory injury (noise, ototoxins, or age-related cochlear damage)

2018 DOI: 10.1080/09546634.2018.1473554

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Sabetta et al., 1 O 2 ), the superoxide radical (O), hydrogen peroxide (H 2 O 2 ) and the hydroxyl radical (OH ), are unavoidable by-products of aerobic metabolism (Foyer and Noctor, 2 O 2 as a component of the Foyer-Halliwell-Asada or ascorbate-glutathione pathway (Noctor and Foyer, As a result of the reversible convertibility between the reduced and the oxidized form and the relatively high concentration of the GSH in the cells, glutathione is one of the most important redox buffers

identified three differentially expressed genes related to ferroptosis through bioinformatics analysis

87 As a result, GSH-related redox signaling may influence how bacteria react to DNA damage, potentially affecting the development of target mutations or modifications in the presence of antibiotic pressure