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Description
The researchers found the rodents exposed to Juul had blood nicotine concentrations 8 times higher than a competing e-cigarette
Nicotine up-regulates expression of orexin and its receptors in rat brain
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For example, in Australia smoking prevalence in females aged 15+ came down from 22.0% in 2000 to 12.4% in 2015 (for males, these numbers were 27 and 14.3%, respectively) [41]
