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Long-Term Effects of Inhalant Use Ulcers in the nose and mouth Frequent nosebleeds Runny nose Reduced appetite Weight loss Cognitive impairments Memory issues Lethargy Apathy Low mood Paranoia Blunted affect Heavy use comes with the risk of developing psychological conditions such as: Depression Anxiety Inhalant induced psychotic Neurocognitive disorders Inhalant intoxication delirium It can also lead to the following physical health problems: Asthma Damage to the lungs Sinusitis Bronchitis Tuberculosis Multi-organ damage Sudden death This kind of drug use can also have teratogenic effects, meaning it can cause changes to a foetus when used during pregnancy

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Drugs that preferentially inhibit the reuptake of norepinephrine such as the tricyclic desipramine and the selective norepinephrine reuptake inhibitor reboxetine are as effective in improving depression scores in depressed patients as specific serotonin reuptake inhibitors (Andreoli et al., 2002

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