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Mucus in the lungs works to trap anything that doesnt belong there, including smoke and other toxins, but too much of the thick fluid can make breathing even more difficult by coating and blocking the small airways within the lungs

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For example, at one point in the film, Teddy Daniels bluntly notes that a few of the guards seem nervous, to which their escort replies, "We all are." At the time, the implication is that their nervousness is over the missing patient and the fact that the hospital is being investigated by government officials

Furthermore, agonists of alpha7-nAChRs, nicotine or GTS-21, reduce cytokine storm mediators such as high mobility group box-1 (HMGB1) [323]