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[205] Side effects Withdrawal symptoms The CDC recognizes seven common nicotine withdrawal symptoms that people often face when stopping smoking: "cravings to smoke, feeling irritated, grouchy, or upset, feeling jumpy and restless, having a hard time concentrating, having trouble sleeping, feeling hungry or gaining weight, or feeling anxious, sad or depressed." [207] Studies have shown that the use of pharmacotherapies, such as varenicline [208] [209] can be useful in reducing withdrawal symptoms during the quitting process

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Pathologist scoring of H&E micrographs demonstrated a strong trend of increased dysplasia scores in mice exposed to CS (Figure 4D)

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