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Smoking is highly attributed with narrowing of the blood-vessels which subsequently trigger high blood pressure and stroke

The bulks are frequently broken and rebuilt over 6-8 weeks, making the tobacco ready for marketing

This, however, was based only on data about male individuals

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a novel bidi with reduced harmful effects comprising a tendu leaf wrapper, tobacco stuffing, said stuffing contained within said wrapping and said wrapping secured, preferably by means of thread or any other means to prevent unfolding of the wrapper preferably made of cotton, such that said bidi is of a shape of a cone cut off at both ends, characterised in that a filter is placed at one end of said bidi, preferably the end with smaller diameter

However, increases in C max values over time for ENDS use, when assessed using similar methods as those used in this Pulze HTS study, have been reported as being less than 25% 69