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The gutkha and khaini users presented that elevated levels of VLDL-C, LDL-C, and were found to be lower levels of HDL-C are the causative agents for the development of coronary artery disease in which LDL-C acts as bad cholesterol and HDL-C acts as good cholesterol

Research specifically linking smoking to hair loss: Su et al., Archives of Dermatology (2007): 740 men smokers had 2x higher prevalence of severe androgenetic alopecia after controlling for age Treb, Dermatology (2003): Identified tobacco smoke-induced free radicals as a direct mechanism for hair follicle damage Fortes et al., British Journal of Dermatology (2005): Smoking significantly increased androgenetic alopecia risk in Italian men and women The evidence is consistent: smoking worsens hair loss