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Significance of the interaction between sex and treatment group was assessed using a drop-in-deviance chi-square test, with the interaction excluded in favor of a main effects model using covariates of only sex and treatment group where appropriate

Launched in 2013

Recent surveys of 15-24 year-olds showed that roughly: 16% had used nicotine pouches 12% were current users 73% of current users also smoke cigarettes Current users were more likely to be age 21+, male and lower income The Health Effects of Nicotine Nicotine use, particularly the chronic or heavy use most often associated with addiction, can affect brain development and lead to long-term disabilities and other health issues

More detailed descriptions of scenario settings can be found in the Supplementary Information

Researchers at Nationwide Childrens Hospital in Ohio analyzed more than a decades worth of data, examining over 134,000 cases of children under 6 who accidentally ingested nicotine through products like vapes, gums, and lozenges