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Inferring biological tasks using Pareto analysis of high-dimensional data

A meta-analysis of published studies10 reported an adjusted relative risk of 6.19 [confidence interval (CI) 4.16-9.21] from 10 studies for chewing betel quid with tobacco

Dev Psychobiol (2011) 53(2):17583

however, overall results are not conclusive

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Impacts of Cigarette Smoking Although cigarette use is declining, it remains a threat to the health of millions around the world