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It cannot be ruled out that nortriptylines effect on the serotonin transporter contributed to its effectiveness as a smoking cessation aid

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[DOI] [PubMed] [Google Scholar] [80].Bloland PB, World Health Organization

A relatively new nicotine product with a tobacco-free and smokeless design has drawn in a wave of new users in just the past year: oral nicotine pouches that sit at the gums and are nearly undetectable when in use

NEW CHALLENGES: DUAL AND MULTIPLE DRUG USE In recent years, numerous investigations have been carried out to specifically identify the harm and consequences of electronic cigarettes since this is a relatively new product, and this trend becomes more complex with the implementation and ease of using these devices with other addictive substances with consequences that can be serious and devastating for public health