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Tobacco-specific nitrosamines (TSNAs), particularly N-nitrosonornicotine (NNN) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), which are present at high concentrations in most smokeless tobacco products, are classified as carcinogenic to humans (Group 1) by the International Agency for Research on Cancer (28)
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However, less is known about these risk factors in African Americans who are disproportionately affected. Participants self-reported their cigarette smoking status through a questionnaire at baseline
