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But that approach is a non-starter for many tobacco opponents

The MR-Egger regression is a technique to detect and correct for horizontal pleiotropy albeit with low power 26

Following accumulation of evidence from controlled trials like the National Lung Screening Trial, major health organizations now recommend annual low-dose CT scanning for lung cancer screening in high risk groups including adults aged 5080 with 20 pack-year smoking history who currently smoke or quit within the past 15 years

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I honestly think a lot of other people would be more pleasant if they did the same

doi: 10.1016/S1474-4422(05)01014-8 [DOI] [PubMed] [Google Scholar] 40