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V/Q mismatch leads to significant hypoxemia

Still, the Taiwan National Audit Office reported that a respectable 34.9 billion sticks were sold across all tobacco companies and their brands in 2015, of which 59.67% were produced locally and 40.33% were imported

[5] Since then, the public perception of tobacco has shifted from that of a harmless product to a clear hazard for the health

[18] Some users will frequently increase their doses to intensify and prolong the euphoric effects

Rouder JN, Engelhardt CR, McCabe S, Morey RD

In terms of volume, Altria estimated the e-vapor category growth of ~35% in 2023, driven by illicit flavored disposable products (now over 50% of the category)