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Compared with the CSE of 3R4F reference cigarettes, a significant decrease was found in the nicotine contents (0.69 mg/cigarette to 0.03 mg/cigarette, Figure 1B) and most minor alkaloids (Figure 1C) in the CSE of the experimental cigarettes

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One study found that 70% of its 1,927 participants were still smoke-free 24 weeks later, compared to just 49.6% of a placebo group