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While only a fraction of that gets inhaled (around 20 mg per pack the rest dissipates in smoke) its important to note that 30 -60 mg of nicotine in its liquid form is lethal for an adult

In studies of colorectal cancer mortality that were included in the meta-analysis, summary RRs were 1.28 (95% CI, 1.151.42) for current smokers based on 14 studies, and 1.23 (95% CI, 1.141.32) for former smokers based on 12 studies (Botteri et al

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Siegel and Cahn note that effectiveness may not hinge on nicotine delivery: Taken together, this evidence suggests that electronic cigarettes are capable of reducing cigarette craving, but that the effect is not due exclusively to nicotine

Please note: As a distributor, it is illegal for you to sell or be in possession of cigarettes (including RYO tobacco) that are not in compliance with the MSA according to R&TC, section 30165.1, unless the product is solely for out-of-state sales