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doi: 10.1016/j.mrrev.2004.02.001

2 Berthold Laufer, "The Introduction of Tobacco into Europe", Field Museum of Natural History, Department of Anthropology, Chicago, Leaflet Number 19 , 1924, p

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and compounds that may reduce the risk of developing alleged smoking-related illnesses.45 RJ Reynolds catalogued and studied mitigants.42 , 53 Many of these compounds can be found within plant additives or as direct chemical additives to cigarettes