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Chronic nicotine treatment increases dopamine levels and reduces dopamine utilization in substantia nigra and in surviving forebrain dopamine nerve terminal systems after a partial di-mesencephalic hemitransection

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Nicotine, the addictive chemical found in tobacco products like cigarettes or vapes, is complex because it acts as both a stimulant and a depressant, depending on the dose, timing, and individual response

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They will almost always feature a draw-fire design (which we will discuss in the next section) and are almost always disposable