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In cluster 2, which interestingly maps to northwestern Iran, both cigarette smoking and tobacco use need to be addressed

[71] In 1947, during the Second Red Scare, she testified as a "friendly witness" before the United States House Committee on Un-American Activities that the 1944 film Song of Russia grossly misrepresented conditions in the Soviet Union, portraying life there as much better and happier than it was

The connection between smoking traditional cigarettes and hearing loss is well-studied

If it is -0.99, then when one goes up the other goes down

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Yes, DNA damage from smoking can lead to birth defects or developmental issues