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Smoking can cause: facial wrinkles, especially around the lips baggy eyelids uneven skin coloring, such as a yellow or gray tone dry, coarse skin temporary yellowing of the fingers and fingernails Smoking reduces how quickly skin repairs itself, increases the risk of skin infections, and increases the severity of skin conditions, including psoriasis

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APR-246 potently inhibits tumour growth and overcomes chemoresistance in preclinical models of oesophageal adenocarcinoma

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