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Specifically, e-vapor increased carcinogen-metabolizing enzymes, such as cytochrome P450 (CYP) family genes and activators of polycyclic aromatic hydrocarbons (PAHs) [25]

For seasoned smokers in particular, purchasing refilled e-cigarettes is a cost-effective option

Long-term inflammation causes remodelling of the airway structure and subsequent restriction in respiratory airflow

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8% year-on-year decline in the 2021-24 period), the financial burden of smoking has grown significantly with manufacturers compensating the volume decline through price hikes

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