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According to most specialized sites, the chances of success using willpower alone are about 1% or 2%
A recent study was done in Taiwan where they followed smokers and non-smokers over an 18 year period

Long term exposed cells at intermediate concentrations were harvested for measurements of mitochondrial function, mtDNA gene expression or mtDNA methylation, specifically at 3.5% (cultured for 4 weeks), 5% (10 weeks), 6% (12 weeks), and 10% (25 weeks)

Quit rates differ between white and Black smokers

Research suggests that frequent adolescent use is associated with lasting changes in brain development that may contribute to difficulties with information processing, memory, attention, and other cognitive functions later in life
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