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In addition, the committee examined in detail a 2016 systematic review that attempted a meta-analysis (Malas et al., 2016), but judged the studies to be too heterogeneous for this to be appropriate

This similarity allows THC to attach to the brains cannabinoid receptors and disrupt the endocannabinoid systems normal functioning

however, additional research is warranted to ascertain the enduring effects, especially considering potential shifts due to evolving circumstances such as the coronavirus disease (COVID-19) pandemic 3,15

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Another study found detectable levels of arsenic, nickel, and other metals in e-liquids, with additional traces of lead in the devices themselves (96)

[23] Joe Sheetz remained president until 2018, when his brother Travis Sheetz was named president and chief operating officer, the first COO in the companys history