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(S)-Nicotine is 428 times more potent than (R)-nicotine in standard nicotinic receptor binding and functional assays and elicits stronger nasal irritation, stinging, and mucosal responses at lower detection thresholdsyet smokers rated it as more pleasant in the only human sensory study

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In terms of physical appearance and quality, we noted no differences between the Backwoods ZaZa and any other edition of the cigars

Its very good and strong