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Indeed, TS exposure for 10 minutes caused vigorous bouts of coughing in conscious guinea pigs, which was inhibited approximately 50% by the cation blocker (ruthenium red) as well as a selective TRPA1 antagonist (HC-030031)

The plasma levonorgestrel and ethinyl estradiol pharmacokinetic profiles following a single dose of two levonorgestrel and ethinyl estradiol tablets are shown in Figure 2

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